Drug developer Shire is the major winner in the Footsie today thanks to its better than expected revenues. Elsewhere, miners are dragged down by the stronger dollar and Anglo American's fall in profits.

Shire has repeated its ambition to secure mid-teen revenue growth on average between 2009 and 2015.

Revenues for the whole of 2009 totalled $3,008m, barely changed from $3,022m in 2008 but ahead of market expectations of around $2,816m. Post-tax income from continuing operations jumped to $503.8m from $170m, but was below some broker forecasts of around $550m. In the first quarter of the current year the group expects revenues and earnings to be behind those seen in the corresponding period of 2009, reflecting the generic competition to Adderall XR, the Attention Deficit Hyperactivity Disorder drug.

The Tullow Oil share price is strong even though the Ugandan government yesterday asked it to reduce its stakes in three oil blocks so ownership of Ugandan oil resources is more diversified.

Anglo American was hit by lower metals prices, but the numbers still came in at the top end of forecasts. The world's largest platinum producer reported earnings before interest, tax, depreciation and amortisation (EBITDA) of $6.93bn, down 41.5% on 2008, as revenue fell 25% to $24.64bn.

Fresnillo, Randgold Resources, Kazakhmys and Eurasian Natural Resources were all in the top 10 fallers.


FTSE 100 - Risers
Shire Plc (SHP) 1,379.00p +5.27%
Tullow Oil (TLW) 1,235.00p +2.15%
British American Tobacco (BATS) 2,213.50p +2.00%
BT Group (BT.A) 118.00p +1.90%
Unilever (ULVR) 1,932.00p +1.90%
Carnival (CCL) 2,374.00p +1.80%
British Sky Broadcasting Group (BSY) 542.50p +1.50%
Imperial Tobacco Group (IMT) 2,064.00p +1.43%
Compass Group (CPG) 475.70p +1.28%
Royal Bank of Scotland Group (RBS) 34.17p +1.27%

FTSE 100 - Fallers
Fresnillo (FRES) 766.00p -2.48%
Wolseley (WOS) 1,434.00p -2.12%
Anglo American (AAL) 2,459.50p -1.70%
Reed Elsevier (REL) 479.00p -1.48%
Lloyds Banking Group (LLOY) 49.94p -1.46%
British Land Co (BLND) 448.00p -1.41%
Randgold Resources (RRS) 4,703.00p -1.30%
Kazakhmys (KAZ) 1,332.00p -1.26%
Eurasian Natural Resources (ENRC) 1,024.00p -1.25%
Hammerson (HMSO) 388.50p -1.15%

Related share prices
Anglo American (AAL) share price
Shire Plc (SHP) share price
Randgold Resources Ltd. (RRS) share price
Tullow Oil (TLW) share price
Kazakhmys (KAZ) share price
Eurasian Natural Resources Corp. (ENRC) share price
Fresnillo (FRES) share price